Literature on SKAP1
SKAP1 [ENSP00000338171]
Src kinase-associated phosphoprotein 1; Positively regulates T-cell receptor signaling by enhancing the MAP kinase pathway. Required for optimal conjugation between T- cells and antigen-presenting cells by promoting the clustering of integrin ITGAL on the surface of T-cells. May be involved in high affinity immunoglobulin epsilon receptor signaling in mast cells. ECO:0000269|PubMed:12652296, ECO:0000269|PubMed:15939789,; Belongs to the SKAP family.
Synonyms: SKAP1, SKAP1p, hSKAP1, J3KS83, J3KSD4 ...