DISEASES

Disease-gene associations mined from literature

Literature on ARID2

ARID2 [ENSP00000335044]

AT-rich interactive domain-containing protein 2; Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Required for the stability of the SWI/SNF chromatin remodeling complex SWI/SNF-B (PBAF). May be involved in targeting the complex to different genes. May be involved in regulating transcriptional activation of cardiac genes.

Synonyms:  ARID2,  ARID2p,  hARID2,  A0A087WY37,  F8VWP4 ...

Linkouts:  STRING  Pharos  UniProt  OMIM