DISEASES

Disease-gene associations mined from literature

Literature on DIAPH2

DIAPH2 [ENSP00000321348]

Protein diaphanous homolog 2; Could be involved in oogenesis. Involved in the regulation of endosome dynamics. Implicated in a novel signal transduction pathway, in which isoform 3 and CSK are sequentially activated by RHOD to regulate the motility of early endosomes through interactions with the actin cytoskeleton; Belongs to the formin homology family. Diaphanous subfamily.

Synonyms:  DIAPH2,  DIAPH2p,  hDIAPH2,  A6NML8,  C9J6U3 ...

Linkouts:  STRING  Pharos  UniProt  OMIM