DISEASES

Disease-gene associations mined from literature

Literature on ZNF106

ZNF106 [ENSP00000263805]

Zinc finger protein 106; RNA-binding protein. Specifically binds to 5'-GGGGCC-3' sequence repeats in RNA. Essential for maintenance of peripheral motor neuron and skeletal muscle function. Required for normal expression and/or alternative splicing of a number of genes in spinal cord and skeletal muscle, including the neurite outgrowth inhibitor RTN4. Also contributes to normal mitochondrial respiratory function in motor neurons, via an unknown mechanism.

Synonyms:  ZNF106,  ZNF106p,  hZNF106,  A0A0C4DGM5,  H3BNJ4 ...

Linkouts:  STRING  Pharos  UniProt