DISEASES

Disease-gene associations mined from literature

Literature on UGGT1

UGGT1 [ENSP00000259253]

UDP-glucose:glycoprotein glucosyltransferase 1; Recognizes glycoproteins with minor folding defects. Reglucosylates single N-glycans near the misfolded part of the protein, thus providing quality control for protein folding in the endoplasmic reticulum. Reglucosylated proteins are recognized by calreticulin for recycling to the endoplasmic reticulum and refolding or degradation.

Synonyms:  UGGT1,  UGGT1p,  hUGGT1,  E2QRN8,  F8WCE6 ...

Linkouts:  STRING  Pharos  UniProt  OMIM