DISEASES

Disease-gene associations mined from literature

Literature on ISG20

ISG20 [ENSP00000306565]

Interferon-stimulated gene 20 kDa protein; Interferon-induced antiviral exoribonuclease that acts on single-stranded RNA and also has minor activity towards single-stranded DNA. Exhibits antiviral activity against RNA viruses including hepatitis C virus (HCV), hepatitis A virus (HAV) and yellow fever virus (YFV) in an exonuclease-dependent manner. May also play additional roles in the maturation of snRNAs and rRNAs, and in ribosome biogenesis.

Synonyms:  ISG20,  ISG20p,  hISG20,  H0YMM4,  H3BLY5 ...

Linkouts:  STRING  Pharos  UniProt  OMIM