Literature on SUMF1
SUMF1 [ENSP00000272902]
Formylglycine-generating enzyme; Oxidase that catalyzes the conversion of cysteine to 3- oxoalanine on target proteins, using molecular oxygen and an unidentified reducing agent (PubMed:12757706, PubMed:15657036, PubMed:15907468, PubMed:25931126, PubMed:16368756, PubMed:21224894). 3- oxoalanine modification, which is also named formylglycine (fGly), occurs in the maturation of arylsulfatases and some alkaline phosphatases that use the hydrated form of 3-oxoalanine as a catalytic nucleophile (PubMed:12757706, PubMed:15657036, PubMed:15907468, PubMed:25931126, PubMed:16368756). Known substrates include GALNS, ARSA, STS and ARSE . ECO:0000269|PubMed:15907468, ECO:0000269|PubMed:16368756,; Belongs to the sulfatase-modifying factor family.
Synonyms: SUMF1, SUMF1p, hSUMF1, E9PF05, F5GXA0 ...