DISEASES

Disease-gene associations mined from literature

Literature on MAPKBP1

MAPKBP1 [ENSP00000393099]

Mitogen-activated protein kinase-binding protein 1; Negative regulator of NOD2 function. It down-regulates NOD2- induced processes such as activation of NF-kappa-B signaling, IL8 secretion and antibacterial response . Involved in JNK signaling pathway (By similarity).

Synonyms:  MAPKBP1,  MAPKBP1p,  hMAPKBP1,  D6R9F7,  D6RAI2 ...

Linkouts:  STRING  Pharos  UniProt