DISEASES

Disease-gene associations mined from literature

Literature on PDZD3

PDZD3 [ENSP00000347742]

Na(+)/H(+) exchange regulatory cofactor NHE-RF4; Acts as a regulatory protein that associates with GUCY2C and negatively modulates its heat-stable enterotoxin-mediated activation . Stimulates SLC9A3 activity in the presence of elevated calcium ions .

Synonyms:  PDZD3,  PDZD3p,  hPDZD3,  B0YJ61,  E9PPZ1 ...

Linkouts:  STRING  Pharos  UniProt  OMIM