DISEASES

Disease-gene associations mined from literature

Literature on CDC42EP5

CDC42EP5 [ENSP00000301200]

Cdc42 effector protein 5; Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts. Inhibits MAPK8 independently of CDC42 binding. Controls septin organization and this effect is negatively regulated by CDC42 (By similarity); Belongs to the BORG/CEP family.

Synonyms:  CDC42EP5,  Q6NZY7,  Q6NZY7p,  hQ6NZY7,  148170 ...

Linkouts:  STRING  Pharos  UniProt  OMIM