Literature on F8A2
F8A2 [ENSP00000358518]
40-kDa huntingtin-associated protein; RAB5A effector molecule that is involved in vesicular trafficking of early endosomes . Mediates the recruitment of HTT by RAB5A onto early endosomes. The HTT- F8A1/F8A2/F8A3-RAB5A complex stimulates early endosomal interaction with actin filaments and inhibits interaction with microtubules, leading to the reduction of endosome motility .
Synonyms: F8A2, F8A2p, hF8A2, F8A1, P23610 ...