DISEASES

Disease-gene associations mined from literature

Literature on PLSCR4

PLSCR4 [ENSP00000347038]

Phospholipid scramblase 4; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system.

Synonyms:  PLSCR4,  PLSCR4p,  hPLSCR4,  C9J3P9,  C9J664 ...

Linkouts:  STRING  Pharos  UniProt  OMIM