DISEASES

Disease-gene associations mined from literature

Literature on TTLL7

TTLL7 [ENSP00000260505]

Tubulin polyglutamylase TTLL7; Polyglutamylase which preferentially modifies beta-tubulin . Mediates both ATP-dependent initiation and elongation of polyglutamylation of microtubules . Required for neurite growth; responsible for the strong increase in tubulin polyglutamylation during postnatal neuronal maturation (By similarity); Belongs to the tubulin--tyrosine ligase family.

Synonyms:  TTLL7,  TTLL7p,  hTTLL7,  A0A087X234,  F2Z2J7 ...

Linkouts:  STRING  Pharos  UniProt