DISEASES

Disease-gene associations mined from literature

Literature on TNS3

TNS3 [ENSP00000312143]

Tensin-3; May play a role in actin remodeling. Involved in the dissociation of the integrin-tensin-actin complex. EGF activates TNS4 and down-regulates TNS3 which results in capping the tail of ITGB1. Seems to be involved in mammary cell migration. May be involved in cell migration and bone development (By similarity); Belongs to the PTEN phosphatase protein family.

Synonyms:  TNS3,  TNS3p,  hTNS3,  C9JHU5,  C9JTD0 ...

Linkouts:  STRING  Pharos  UniProt  OMIM