DISEASES

Disease-gene associations mined from literature

Literature on LEMD3

LEMD3 [ENSP00000308369]

Inner nuclear membrane protein Man1; Can function as a specific repressor of TGF-beta, activin, and BMP signaling through its interaction with the R-SMAD proteins. Antagonizes TGF-beta-induced cell proliferation arrest.

Synonyms:  LEMD3,  LEMD3p,  hLEMD3,  A0A024RBB9,  Q9Y2U8 ...

Linkouts:  STRING  Pharos  UniProt  OMIM