DISEASES

Disease-gene associations mined from literature

Literature on PLSCR1

PLSCR1 [ENSP00000345494]

Phospholipid scramblase 1; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system.

Synonyms:  PLSCR1,  PLSCR1p,  hPLSCR1,  C9J0H3,  C9J7K9 ...

Linkouts:  STRING  Pharos  UniProt  OMIM