DISEASES

Disease-gene associations mined from literature

Literature on SYT3

SYT3 [ENSP00000340914]

Synaptotagmin-3; Ca(2+) sensor involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain. Ca(2+) induces binding of the C2-domains to phospholipid membranes and to assembled SNARE-complexes; both actions contribute to triggering exocytosis (By similarity). Plays a role in dendrite formation by melanocytes .

Synonyms:  SYT3,  SYT3p,  hSYT3,  A0A024R4I9,  M0QY70 ...

Linkouts:  STRING  Pharos  UniProt  OMIM