DISEASES

Disease-gene associations mined from literature

Literature on GTF3A

GTF3A [ENSP00000370532]

Transcription factor IIIA; Involved in ribosomal large subunit biogenesis. Binds the approximately 50 base pairs internal control region (ICR) of 5S ribosomal RNA genes. It is required for their RNA polymerase III- dependent transcription and may also maintain the transcription of other genes . Also binds the transcribed 5S RNA's (By similarity).

Synonyms:  GTF3A,  GTF3Ap,  hGTF3A,  A0A1X7SBT5,  H7BZ51 ...

Linkouts:  STRING  Pharos  UniProt  OMIM