DISEASES

Disease-gene associations mined from literature

Literature on FGD1

FGD1 [ENSP00000364277]

FYVE, RhoGEF and PH domain-containing protein 1; Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Plays a role in regulating the actin cytoskeleton and cell shape.

Synonyms:  FGD1,  FGD1p,  hFGD1,  A0A024R9Y5,  P98174 ...

Linkouts:  STRING  Pharos  UniProt  OMIM