DISEASES

Disease-gene associations mined from literature

Literature on SLC25A27

SLC25A27 [ENSP00000360398]

Mitochondrial uncoupling protein 4; UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation from ATP synthesis. As a result, energy is dissipated in the form of heat. May play a role in thermoregulatory heat production and metabolism in brain; Belongs to the mitochondrial carrier (TC 2.A.29) family.

Synonyms:  SLC25A27,  O95847,  Q5VTS8,  S4R300,  S4R3J2 ...

Linkouts:  STRING  Pharos  UniProt  OMIM