DISEASES

Disease-gene associations mined from literature

Literature on SRCAP

SRCAP [ENSP00000262518]

Helicase SRCAP; Catalytic component of the SRCAP complex which mediates the ATP-dependent exchange of histone H2AZ/H2B dimers for nucleosomal H2A/H2B, leading to transcriptional regulation of selected genes by chromatin remodeling. Acts as a coactivator for CREB-mediated transcription, steroid receptor-mediated transcription, and Notch- mediated transcription. ECO:0000269|PubMed:11522779, ECO:0000269|PubMed:14500758, ECO:0000269|PubMed:16024792, ECO:0000269|PubMed:16634648,; Belongs to the SNF2/RAD54 helicase family. SWR1 subfamily.

Synonyms:  SRCAP,  A0A087X0E3,  A0A0A0MS59,  C9J4U4,  Q6ZRS2 ...

Linkouts:  STRING  Pharos  UniProt  OMIM