DISEASES

Disease-gene associations mined from literature

Literature on ADI1

ADI1 [ENSP00000333666]

1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Also down-regulates cell migration mediated by MMP14. Necessary for hepatitis C virus replication in an otherwise non- permissive cell line.

Synonyms:  ADI1,  ADI1p,  hADI1,  H7C382,  Q9BV57 ...

Linkouts:  STRING  Pharos  UniProt  OMIM