Literature on TAS2R4
TAS2R4 [ENSP00000247881]
Taste receptor type 2 member 4; Gustducin-coupled receptor for denatonium and N(6)-propyl-2- thiouracil implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5. In airway epithelial cells, binding of denatonium increases the intracellular calcium ion concentration and stimulates ciliary beat frequency.
Synonyms: TAS2R4, TAS2R4p, hTAS2R4, Q9NYW5, Q9NYW5p ...