DISEASES

Disease-gene associations mined from literature

Literature on IRF2BP2

IRF2BP2 [ENSP00000355568]

Interferon regulatory factor 2-binding protein 2; Acts as a transcriptional corepressor in a IRF2-dependent manner; this repression is not mediated by histone deacetylase activities . Represses the NFAT1-dependent transactivation of NFAT-responsive promoters . Acts as a coactivator of VEGFA expression in cardiac and skeletal muscles . Plays a role in immature B-cell differentiation . ECO:0000269|PubMed:20702774, ECO:0000269|PubMed:21576369,

Synonyms:  IRF2BP2,  IRF2BP2p,  hIRF2BP2,  Q7Z5L9,  Q7Z5L9p ...

Linkouts:  STRING  Pharos  UniProt  OMIM