DISEASES

Disease-gene associations mined from literature

Literature on ERFE

ERFE [ENSP00000442304]

Erythroferrone; Iron-regulatory hormone that acts as an erythroid regulator after hemorrhage: produced by erythroblasts following blood loss and mediates suppression of hepcidin (HAMP) expression in the liver, thereby promoting increased iron absorption and mobilization from stores. Promotes lipid uptake into adipocytes and hepatocytes via transcriptional up-regulation of genes involved in fatty acid uptake. ; Belongs to the adipolin/erythroferrone family.

Synonyms:  ERFE,  H0Y2X4,  H7BY19,  Q4G0M1,  H0Y2X4p ...

Linkouts:  STRING  Pharos  UniProt  OMIM