DISEASES

Disease-gene associations mined from literature

Literature on DYNLT3

DYNLT3 [ENSP00000367841]

Dynein light chain Tctex-type 3; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Probably binds BUB3 as part of transport cargo. Required for the efficient progression through mitosis (By similarity); Belongs to the dynein light chain Tctex-type family.

Synonyms:  DYNLT3,  DYNLT3p,  hDYNLT3,  A6NGJ0,  F2Z328 ...

Linkouts:  STRING  Pharos  UniProt  OMIM