DISEASES

Disease-gene associations mined from literature

Literature on HSD17B11

HSD17B11 [ENSP00000351035]

Estradiol 17-beta-dehydrogenase 11; Can convert androstan-3-alpha,17-beta-diol (3-alpha-diol) to androsterone in vitro, suggesting that it may participate in androgen metabolism during steroidogenesis. May act by metabolizing compounds that stimulate steroid synthesis and/or by generating metabolites that inhibit it. Has no activity toward DHEA (dehydroepiandrosterone), or A- dione (4-androste-3,17-dione), and only a slight activity toward testosterone to A-dione. Tumor-associated antigen in cutaneous T-cell lymphoma.

Synonyms:  HSD17B11,  D6RCD0,  Q8NBQ5,  D6RCD0p,  hD6RCD0 ...

Linkouts:  STRING  Pharos  UniProt  OMIM