DISEASES

Disease-gene associations mined from literature

Literature on TMPRSS15

TMPRSS15 [ENSP00000284885]

Enteropeptidase non-catalytic heavy chain; Responsible for initiating activation of pancreatic proteolytic proenzymes (trypsin, chymotrypsin and carboxypeptidase A). It catalyzes the conversion of trypsinogen to trypsin which in turn activates other proenzymes including chymotrypsinogen, procarboxypeptidases, and proelastases.

Synonyms:  TMPRSS15,  E9PG70,  P98073,  E9PG70p,  hE9PG70 ...

Linkouts:  STRING  Pharos  UniProt  OMIM