Literature on TAS2R46
TAS2R46 [ENSP00000436450]
Taste receptor type 2 member 46; Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity). In airway epithelial cells, binding of bitter compounds increases the intracellular calcium ion concentration and stimulates ciliary beat frequency (By similarity); Belongs to the G-protein coupled receptor T2R family.
Synonyms: TAS2R46, TAS2R46p, hTAS2R46, P59540, P59540p ...