DISEASES

Disease-gene associations mined from literature

Literature on FAM120A

FAM120A [ENSP00000277165]

Constitutive coactivator of PPAR-gamma-like protein 1; May participate in mRNA transport in the cytoplasm (By similarity). Critical component of the oxidative stress-induced survival signaling. Activates src family kinases and acts as a scaffolding protein enabling src family kinases to phosphorylate and activate PI3-kinase. Binds RNA and promotes the secretion of IGF-II. May play a pivotal role in the progression of scirrhous-type gastric cancer by supporting cancer cell survival in environments with various oxidative stresses.

Synonyms:  FAM120A,  FAM120Ap,  hFAM120A,  A0A0C4DG79,  A0A0C4DH52 ...

Linkouts:  STRING  Pharos  UniProt  OMIM