DISEASES

Disease-gene associations mined from literature

Literature on RAB25

RAB25 [ENSP00000354376]

Ras-related protein Rab-25; Involved in the regulation of cell survival. Promotes invasive migration of cells in which it functions to localize and maintain integrin alpha-V/beta-1 at the tips of extending pseudopodia . Involved in the regulation of epithelial morphogenesis through the control of CLDN4 expression and localization at tight junctions (By similarity). May selectively regulate the apical recycling pathway. Together with MYO5B regulates transcytosis (By similarity). ECO:0000250|UniProtKB:P46629, ECO:0000250|UniProtKB:Q9WTL2,; Belongs to the small GTPase superfamily. Rab family.

Synonyms:  RAB25,  RAB25p,  hRAB25,  P57735,  P57735p ...

Linkouts:  STRING  Pharos  UniProt  OMIM