DISEASES

Disease-gene associations mined from literature

Literature on STXBP5

STXBP5 [ENSP00000321826]

Syntaxin-binding protein 5; Plays a regulatory role in calcium-dependent exocytosis and neurotransmitter release. Inhibits membrane fusion between transport vesicles and the plasma membrane. May modulate the assembly of trans- SNARE complexes between transport vesicles and the plasma membrane. Inhibits translocation of GLUT4 from intracellular vesicles to the plasma membrane. Competes with STXBP1 for STX1 binding (By similarity). ; Belongs to the WD repeat L(2)GL family.

Synonyms:  STXBP5,  STXBP5p,  hSTXBP5,  H0Y332,  Q3B794 ...

Linkouts:  STRING  Pharos  UniProt  OMIM