DISEASES

Disease-gene associations mined from literature

Literature on SLC9C1

SLC9C1 [ENSP00000306627]

Sodium/hydrogen exchanger 10; Sperm-specific sodium/hydrogen exchanger involved in intracellular pH regulation of spermatozoa. Required for sperm motility and fertility. Involved in sperm cell hyperactivation, a step needed for sperm motility which is essential late in the preparation of sperm for fertilization. Required for the expression and bicarbonate regulation of the soluble adenylyl cyclase (sAC) (By similarity).

Synonyms:  SLC9C1,  SLC9C1p,  hSLC9C1,  C9J3M6,  F8WCJ0 ...

Linkouts:  STRING  Pharos  UniProt