DISEASES

Disease-gene associations mined from literature

Literature on CD300A

CD300A [ENSP00000353259]

CMRF35-like molecule 8; Inhibitory receptor which may contribute to the down- regulation of cytolytic activity in natural killer (NK) cells, and to the down-regulation of mast cell degranulation (PubMed:10746781, PubMed:16339535, PubMed:9701027). Negatively regulates the Toll-like receptor (TLR) signaling mediated by MYD88 but not TRIF through activation of PTPN6 . ECO:0000269|PubMed:16339535, ECO:0000269|PubMed:22043923,; Belongs to the CD300 family.

Synonyms:  CD300A,  CD300Ap,  hCD300A,  J3QKQ4,  Q9UGN4 ...

Linkouts:  STRING  Pharos  UniProt  OMIM