DISEASES

Disease-gene associations mined from literature

Literature on NEK8

NEK8 [ENSP00000268766]

Serine/threonine-protein kinase Nek8; Required for renal tubular integrity. May regulate local cytoskeletal structure in kidney tubule epithelial cells. May regulate ciliary biogenesis through targeting of proteins to the cilia (By similarity). Plays a role in organogenesis and is involved in the regulation of the Hippo signaling pathway; Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.

Synonyms:  NEK8,  NEK8p,  hNEK8,  K7EL04,  K7EMF0 ...

Linkouts:  STRING  Pharos  UniProt  OMIM