DISEASES

Disease-gene associations mined from literature

Literature on MASP2

MASP2 [ENSP00000383690]

Mannan-binding lectin serine protease 2 A chain; Serum protease that plays an important role in the activation of the complement system via mannose-binding lectin. After activation by auto-catalytic cleavage it cleaves C2 and C4, leading to their activation and to the formation of C3 convertase.

Synonyms:  MASP2,  MASP2p,  hMASP2,  O00187,  O00187p ...

Linkouts:  STRING  Pharos  UniProt  OMIM