DISEASES

Disease-gene associations mined from literature

Literature on LRRC34

LRRC34 [ENSP00000414635]

Leucine-rich repeat-containing protein 34; Highly expressed in stem cells where it may be involved in regulation of pluripotency. In embryonic stem cells (ESCs), important for normal expression of the pluripotency regulators POU5F1/OCT4 and KLF4. Also important for expression of the ectodermal marker gene NES and the endodermal marker gene GATA4. Promotes stem cell proliferation in vitro.

Synonyms:  LRRC34,  LRRC34p,  hLRRC34,  G3V115,  H0YEZ4 ...

Linkouts:  STRING  Pharos  UniProt