Literature on PEG3
PEG3 [ENSP00000326581]
Paternally-expressed gene 3 protein; Induces apoptosis in cooperation with SIAH1A. Acts as a mediator between p53/TP53 and BAX in a neuronal death pathway that is activated by DNA damage. Acts synergistically with TRAF2 and inhibits TNF induced apoptosis through activation of NF-kappa-B (By similarity). Possesses a tumor suppressing activity in glioma cells; Belongs to the krueppel C2H2-type zinc-finger protein family.
Synonyms: PEG3, PEG3p, hPEG3, A0A3B3IRU6, A0A3B3ISL2 ...