DISEASES

Disease-gene associations mined from literature

Literature on SP8

SP8 [ENSP00000408792]

Transcription factor Sp8; Transcription factor which plays a key role in limb development. Positively regulates FGF8 expression in the apical ectodermal ridge (AER) and contributes to limb outgrowth in embryos (By similarity); Belongs to the Sp1 C2H2-type zinc-finger protein family.

Synonyms:  SP8,  SP8p,  hSP8,  A0A087X0Q6,  Q8IXZ3 ...

Linkouts:  STRING  Pharos  UniProt  OMIM