Literature on TONSL
TONSL [ENSP00000386239]
Tonsoku-like protein; Component of the MMS22L-TONSL complex, a complex that stimulates the recombination-dependent repair of stalled or collapsed replication forks. The MMS22L-TONSL complex is required to maintain genome integrity during DNA replication by promoting homologous recombination-mediated repair of replication fork-associated double- strand breaks. It may act by mediating the assembly of RAD51 filaments on ssDNA. Within the complex, may act as a scaffold. ECO:0000269|PubMed:21055985, ECO:0000269|PubMed:30773278,; Belongs to the Tonsoku family.
Synonyms: TONSL, A0A087X1F6, Q96HA7, Q96HA7p, hQ96HA7 ...