DISEASES

Disease-gene associations mined from literature

Literature on E2F2

E2F2 [ENSP00000355249]

Transcription factor E2F2; Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from g1 to s phase. E2F2 binds specifically to RB1 in a cell-cycle dependent manner; Belongs to the E2F/DP family.

Synonyms:  E2F2,  E2F2p,  hE2F2,  Q14209,  Q14209p ...

Linkouts:  STRING  Pharos  UniProt  OMIM