DISEASES

Disease-gene associations mined from literature

Literature on ZNF219

ZNF219 [ENSP00000354206]

Zinc finger protein 219; Transcriptional regulator . Recognizes and binds 2 copies of the core DNA sequence motif 5'-GGGGG- 3' . Binds to the HMGN1 promoter and may repress HMGN1 expression . Regulates SNCA expression in primary cortical neurons . Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with SOX9 (By similarity). Plays a role in chondrocyte differentiation (By similarity); Belongs to the krueppel C2H2-type zinc-finger protein family.

Synonyms:  ZNF219,  ZNF219p,  hZNF219,  G3V2E3,  G3V2Q8 ...

Linkouts:  STRING  Pharos  UniProt  OMIM