Literature on ACSS1
ACSS1 [ENSP00000316924]
Acetyl-coenzyme A synthetase 2-like, mitochondrial; Catalyzes the synthesis of acetyl-CoA from short-chain fatty acids . Acetate is the preferred substrate . Can also utilize propionate with a much lower affinity (By similarity). Provides acetyl-CoA that is utilized mainly for oxidation under ketogenic conditions (By similarity). Involved in thermogenesis under ketogenic conditions, using acetate as a vital fuel when carbohydrate availability is insufficient (By similarity).
Synonyms: ACSS1, ACSS1p, hACSS1, Q5TF43, Q9NUB1 ...