DISEASES

Disease-gene associations mined from literature

Literature on METAP1D

METAP1D [ENSP00000315152]

Methionine aminopeptidase 1D, mitochondrial; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed (By similarity). May play a role in colon tumorigenesis; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.

Synonyms:  METAP1D,  METAP1Dp,  hMETAP1D,  Q6UB28,  Q6UB28p ...

Linkouts:  STRING  Pharos  UniProt