DISEASES

Disease-gene associations mined from literature

Literature on IL12RB2

IL12RB2 [ENSP00000262345]

Interleukin-12 receptor subunit beta-2; Receptor for interleukin-12. This subunit is the signaling component coupling to the JAK2/STAT4 pathway. Promotes the proliferation of T-cells as well as NK cells. Induces the promotion of T-cells towards the Th1 phenotype by strongly enhancing IFN-gamma production.

Synonyms:  IL12RB2,  IL12RB2p,  hIL12RB2,  A0A0A0MTN7,  H0Y5V0 ...

Linkouts:  STRING  Pharos  UniProt  OMIM