DISEASES

Disease-gene associations mined from literature

Literature on NASP

NASP [ENSP00000255120]

Nuclear autoantigenic sperm protein; Required for DNA replication, normal cell cycle progression and cell proliferation. Forms a cytoplasmic complex with HSP90 and H1 linker histones and stimulates HSP90 ATPase activity. NASP and H1 histone are subsequently released from the complex and translocate to the nucleus where the histone is released for binding to DNA.

Synonyms:  NASP,  E9PAU3,  E9PI86,  E9PJQ2,  E9PKR5 ...

Linkouts:  STRING  Pharos  UniProt  OMIM