DISEASES

Disease-gene associations mined from literature

Literature on FLRT1

FLRT1 [ENSP00000246841]

Leucine-rich repeat transmembrane protein FLRT1; Plays a role in fibroblast growth factor-mediated signaling cascades that lead to the activation of MAP kinases. Promotes neurite outgrowth via FGFR1-mediated activation of downstream MAP kinases. Promotes an increase both in neurite number and in neurite length. May play a role in cell-cell adhesion and cell guidance via its interaction with ADGRL1/LPHN1 and ADGRL3.

Synonyms:  FLRT1,  FLRT1p,  hFLRT1,  Q9NZU1,  Q9NZU1p ...

Linkouts:  STRING  Pharos  UniProt  OMIM