DISEASES

Disease-gene associations mined from literature

Literature on NECAB3

NECAB3 [ENSP00000246190]

N-terminal EF-hand calcium-binding protein 3; Inhibits the interaction of APBA2 with amyloid-beta precursor protein (APP), and hence allows formation of amyloid-beta. May enhance the activity of HIF1A and thus promote glycolysis under normoxic conditions; the function requires its ABM domain and may implicate the stabilization of the interaction between HIF1AN and APBA3.

Synonyms:  NECAB3,  NECAB3p,  hNECAB3,  Q96P71,  U3KPZ3 ...

Linkouts:  STRING  Pharos  UniProt  OMIM