DISEASES

Disease-gene associations mined from literature

Literature on COA3

COA3 [ENSP00000354762]

Cytochrome c oxidase assembly factor 3 homolog, mitochondrial; Core component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, that regulates cytochrome c oxidase assembly. MITRAC complexes regulate both translation of mitochondrial encoded components and assembly of nuclear-encoded components imported in mitochondrion. Required for efficient translation of MT-CO1 and mitochondrial respiratory chain complex IV assembly; Belongs to the COA3 family.

Synonyms:  COA3,  COA3p,  hCOA3,  A0A024R1X4,  K7EPV0 ...

Linkouts:  STRING  Pharos  UniProt