DISEASES

Disease-gene associations mined from literature

Literature on RAD21L1

RAD21L1 [ENSP00000386414]

Double-strand-break repair protein rad21-like protein 1; Meiosis-specific component of some cohesin complex required during the initial steps of prophase I in male meiosis. Probably required during early meiosis in males for separation of sister chromatids and homologous chromosomes. Replaces RAD21 in premeiotic S phase (during early stages of prophase I), while RAD21 reappears in later stages of prophase I. Involved in synaptonemal complex assembly, synapsis initiation and crossover recombination between homologous chromosomes during prophase I (By similarity).

Synonyms:  RAD21L1,  RAD21L1p,  hRAD21L1,  A0A140T8W2,  Q9H4I0 ...

Linkouts:  STRING  Pharos  UniProt